OXYTOCIC POLYPEPTIDES IN HUMAN URINE

Oxytocic Action of Neptal

The cardiovascular effects of oxytocic drugs.

The effects of ergometrine 0.5 mg i.v. and of synthetic oxytocin 5 units i.v. on the alpha and the beta adrenoceptive blood vessels of the foreann have been studied by means of volume-pulse plethysmography in 40 gynaecological patients. Ergometrine constricted the alpha and the beta blood vessels. It is thought that the widespread vasoconstriction may precipitate post-partum hypertension or pul...

Ergot of Rye as an Oxytocic

tioners were frequently in the habit of giving it to hasten tedious labour that was occasioned solely by the presence of some mechanical obstacle. In this way they invoked and called to their aid the powers, as Dr. Barnes has remarked, of a Frankenstein, quite beyond their control, whose unbridled strength might give rise to frightful disasters; in their ignorance they quite forgot that the pro...

Hydroxylysine glycosides in human urine.

Hyd roxylysyl-galactosyl-glucose (HGG) and hyd roxylysyl-galactose (HG) were isolated from normal human urine and shown to be identical with hydroxylysine glycosides (OHLG’s) whose structure had been elucidated in other laboratories. We devised a procedure for separating the OHLG’s from many other urinary constituents by preliminary fractionation on a column of Sephadex. The OHLG’s in the fract...

Acid in Human Determination Urine

An ion pair reversed phase HPLC method for the determination of clavulanic acid has been developed. Since clavulanic acid had poor absorption O,mas 201 nm in water) in a UVregion suitable for HPLC detection, the detectability was enhanced by bathochromic shift of )maa due to solvent effect. The shifts of 2ma.., were measured with the solutions containing clavulanic acid, tetrabutylammonium brom...